How Do You Spell AER I BETA LACTAMASE?

1. AER I beta-Lactamase is an enzyme that belongs to the class C β-lactamases, which are enzymes primarily produced by bacteria that provide resistance against β-lactam antibiotics like penicillins, cephalosporins, and carbapenems. The AER I beta-lactamase is commonly found in Acinetobacter species, a group of gram-negative bacteria that are well-known for their ability to cause opportunistic infections in hospital settings.

   This specific type of beta-lactamase, AER I, possesses the characteristic ability to hydrolyze a wide range of β-lactam antibiotics due to modifications in its active site, rendering these clinically important drugs ineffective. The AER I beta-lactamase is inherently resistant to many inhibitors that are typically used to counteract the activity of other β-lactamases, making it difficult to treat bacterial infections caused by Acinetobacter strains producing this enzyme.

   The production of AER I beta-lactamase often occurs due to gene mutations or gene acquisition via horizontal transfer from other bacteria. This genetic flexibility further contributes to the spread of antibiotic resistance in healthcare settings and poses a significant challenge in the treatment of Acinetobacter infections. In summary, AER I beta-lactamase is an enzyme produced by Acinetobacter species that hydrolyzes a broad range of β-lactam antibiotics, leading to increased antibiotic resistance and making these bacteria difficult to treat.

Common Misspellings for AER I BETA LACTAMASE

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