IFG stands for Insulin-like Growth Factor. It is a protein hormone produced primarily by the liver in response to the release of human growth hormone (HGH) from the pituitary gland. IFG plays a crucial role in stimulating cell growth and division, particularly in bone, muscle, and other body tissues during childhood and adolescence.
IFG belongs to a family of hormones called growth factors, which are essential for normal growth and development. It works by binding to specific receptors on target cells, activating signaling pathways that promote cell proliferation, differentiation, and survival. In addition to its role in growth, IFG also regulates various metabolic processes, including glucose metabolism and lipid synthesis.
The levels of IFG in the body are tightly regulated and may vary depending on age, sex, and physiological conditions. Excessive or insufficient levels of IFG can lead to growth disorders, such as dwarfism or acromegaly. IFG is commonly measured in clinical practice as part of diagnostic tests for growth disorders or to monitor the response to growth hormone therapy.
IFG has also gained interest in recent years due to its potential role in aging, disease development, and cancer. Research suggests that elevated levels of IFG may be associated with an increased risk of certain types of cancer, including breast, prostate, and colorectal cancer. Furthermore, IFG is believed to interact with insulin and contribute to insulin resistance, a key feature of type 2 diabetes.
