DISTOMER Meaning and
Definition
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A distomer refers to an enantiomeric stereoisomer that is structurally similar to but not identical with the desired biologically active compound. It is a term commonly used in chemistry and pharmacology to describe stereoisomers that exhibit mirror-image asymmetry and possess similar chemical structures, yet differ in their chiral centers. Distomers can arise during the process of synthesizing pharmaceutical drugs, where the desired compound often must be produced in its purest enantiomeric form due to the distinct biological activities of the enantiomers.
In pharmacological research, distomers are considered as unwanted by-products or impurities that must be eliminated to ensure the efficacy and safety of the drug. This is because distomers may possess different pharmacological properties and interact with the body in a dissimilar manner compared to the desired compound. The existence of distomers can introduce complexities during drug development and manufacturing, as their presence may potentially result in decreased effectiveness, increased side effects, or other undesirable effects.
To address this issue, extensive analysis and purification techniques are employed to separate the desired compound from its distomers. It is crucial to identify and eliminate distomers to ensure that a drug exhibits the intended therapeutic properties and to minimize potential adverse effects. Therefore, the accurate identification and separation of distomers play a pivotal role in pharmaceutical research and manufacturing processes.
Common Misspellings for DISTOMER
- distomr
- distomes
- distomed
- distomre
- distomer
- distome4
- distomee
- distome
- sistomer
- xistomer
- cistomer
- fistomer
- ristomer
- eistomer
- dustomer
- djstomer
- dkstomer
- dostomer
- d9stomer
- d8stomer
Etymology of DISTOMER
The word "distomer" is derived from the Latin term "distorqueo", which means "to distort" or "to twist". The prefix "di-" in "distomer" signifies "apart" or "twice", indicating a twisting or distortion of a molecule. In the context of chemistry, a distomer refers to one of two enantiomers (mirror image forms) of a chiral molecule that differ in their spatial arrangement and exhibit different biological or chemical properties.
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