ACETYLMURAMYL ALANYL ISOGLUTAMINE Meaning and
Definition
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Acetylmuramyl alanyl isoglutamine (MurNAc-Ala-Glu) is a small peptide molecule that plays a crucial role in the immune system's defense against microbial infections. It is a component of bacterial cell wall peptidoglycan, a complex structure that forms the outermost layer of many bacteria.
In the context of the immune system, acetylmuramyl alanyl isoglutamine acts as a potent immunostimulant or immunomodulator. It can activate various immune cells, such as macrophages and natural killer cells, by interacting with specific receptors known as pattern recognition receptors (PRRs). This interaction leads to the production of pro-inflammatory cytokines, which are essential for mounting an effective immune response against infections.
The presence of acetylmuramyl alanyl isoglutamine in the body is detected by PRRs, such as NOD-like receptors and Toll-like receptors, which are expressed on the surface of immune cells. Binding of this molecule to these receptors triggers a signaling cascade, ultimately leading to the activation of transcription factors and the release of cytokines in a controlled manner.
Acetylmuramyl alanyl isoglutamine is also widely used in experimental immunology as an adjuvant, amplifying the immune response to antigens. Adjuvants are substances that are co-administered with vaccines or immunotherapeutic agents to enhance their effectiveness by promoting a stronger and more durable immune response.
In summary, acetylmuramyl alanyl isoglutamine is a small peptide molecule derived from bacterial cell walls. It acts as a potent immunostimulant, activating the immune system and enhancing the immune response against infections.
Common Misspellings for ACETYLMURAMYL ALANYL ISOGLUTAMINE
- zcetylmuramyl alanyl isoglutamine
- scetylmuramyl alanyl isoglutamine
- wcetylmuramyl alanyl isoglutamine
- qcetylmuramyl alanyl isoglutamine
- axetylmuramyl alanyl isoglutamine
- avetylmuramyl alanyl isoglutamine
- afetylmuramyl alanyl isoglutamine
- adetylmuramyl alanyl isoglutamine
- acwtylmuramyl alanyl isoglutamine
- acstylmuramyl alanyl isoglutamine
- acdtylmuramyl alanyl isoglutamine
- acrtylmuramyl alanyl isoglutamine
- ac4tylmuramyl alanyl isoglutamine
- ac3tylmuramyl alanyl isoglutamine
- acerylmuramyl alanyl isoglutamine
- acefylmuramyl alanyl isoglutamine
- acegylmuramyl alanyl isoglutamine
- aceyylmuramyl alanyl isoglutamine
- ace6ylmuramyl alanyl isoglutamine
- ace5ylmuramyl alanyl isoglutamine
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