ACETOXYHYDROXYACID SYNTHASE III Meaning and
Definition
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Acetoxyhydroxyacid Synthase III is an enzyme that plays a critical role in the biosynthetic pathway for the production of branched chain amino acids (BCAAs) in microorganisms and plants. It catalyzes the condensation of acetyl-CoA, as well as hydroxyalkylthiamine diphosphate (HTP), to form acetoxyalkylthiamine diphosphate (AATP). This essential step in the pathway leads to the production of α-keto acids, which are subsequently converted into BCAAs.
The enzyme Acetoxyhydroxyacid Synthase III is part of a larger family of enzymes known as pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multienzyme complexes. It consists of multiple subunits, each with specific domains responsible for various enzymatic activities required for BCAA synthesis. This enzyme is highly regulated and its activity is influenced by factors such as feedback inhibition by BCAAs and other metabolites.
Understanding the function of Acetoxyhydroxyacid Synthase III is important for agricultural and pharmaceutical research. Mutations in this enzyme can lead to altered BCAA synthesis pathways, affecting the growth and development of microorganisms and plants. By studying the structure and activity of this enzyme, scientists can gain insights into the regulation of BCAA biosynthesis and potentially develop strategies to enhance or inhibit BCAA production for agricultural purposes or therapeutic applications.
Common Misspellings for ACETOXYHYDROXYACID SYNTHASE III
- zcetoxyhydroxyacid synthase iii
- scetoxyhydroxyacid synthase iii
- wcetoxyhydroxyacid synthase iii
- qcetoxyhydroxyacid synthase iii
- axetoxyhydroxyacid synthase iii
- avetoxyhydroxyacid synthase iii
- afetoxyhydroxyacid synthase iii
- adetoxyhydroxyacid synthase iii
- acwtoxyhydroxyacid synthase iii
- acstoxyhydroxyacid synthase iii
- acdtoxyhydroxyacid synthase iii
- acrtoxyhydroxyacid synthase iii
- ac4toxyhydroxyacid synthase iii
- ac3toxyhydroxyacid synthase iii
- aceroxyhydroxyacid synthase iii
- acefoxyhydroxyacid synthase iii
- acegoxyhydroxyacid synthase iii
- aceyoxyhydroxyacid synthase iii
- ace6oxyhydroxyacid synthase iii
- ace5oxyhydroxyacid synthase iii
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